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Safety and Dosage of GutGard™
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| Safety |
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The Salmonella typhimurium reverse mutation assay |
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Salmonella reverse mutation assay was conducted to test the mutagenic potential of GutGard™ using S. typhimurium tester strains viz., TA98 and TAMix. GutGard™ was tested at the concentrations of 501, 158, 50, 16, 5 and 1.6 µg/ml using dimethyl sulfoxide (DMSO) as solvent and with and without the metabolic activation (S9 fraction).
GutGard™ did not induce mutation both in the presence and absence of metabolic activation in S. typhimurium mutant strains TA98 and TAMix at all the concentrations tested. This study suggests that GutGard™ is non-mutagenic up to a concentration of 501 µg/ml. |
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Acute oral toxicity study |
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Acute oral toxicity study was conducted on GutGard™ in female albino Wistar rats. Administration of 5000 mg/kg body weight of GutGard™ neither showed mortality nor abnormal clinical signs, indicating its safety after oral administration as a single dose up to 5000 mg/kg b.w. |
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| Dosage |
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For adult – 150-300 mg/day in two divided doses. |
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Enquire About GutGard™
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| NATURAL REMEDIES PVT. LTD. |
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Plot No. 5B,
Veerasandra Industrial Area,
19th K.M. Stone, Hosur Road,
Electronic City (Post),
Bangalore - 560 100,
Karnataka, India.
 +91-80-4020 9999
 info@naturalremedy.com |
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Why GutGard™? 